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We need better guidelines to deal with age-related muscle loss

By December 4, 2018 January 27th, 2021 Article
deal with age related muscle loss

 

By Alex Hutchinson | Special to the Globe and Mail

You might be relieved to hear that the creeping weight gain of middle age – a pound or two (0.5 to 1 kilogram) a year starting in your 20s, on average – eventually grinds to a halt. By the time you’re in your 50s, you’ll typically start slowly shedding weight.

Don’t celebrate yet, though. There’s a good chance that the weight you’re losing is muscle – precisely what you need to hang onto to stay metabolically healthy and independent into old age. The scientific term for this age-related loss of muscle, strength and physical function is “sarcopenia,” a condition that’s often overshadowed by the more urgent battle against obesity – and that oversight, according to a new review paper by Canadian researchers, has potentially serious consequences.

“The aging of the population is the epidemiological trend of our time,” says Camila Oliveira, a nutrition researcher at the University of Alberta. “We know that sedentary lifestyles, poor dietary patterns and increasing life expectancy will dramatically impact the prevalence of sarcopenia in the next decade.”

In a forthcoming issue of the journal Applied Physiology, Nutrition, and Metabolism, Oliveira and her colleague Carla Prado, along with Isabelle Dionne of the University of Sherbrooke, argue that current Canadian nutrition and exercise guidelines are inadequate for preventing sarcopenia and don’t reflect the latest research on the topic. Guidelines for protein intake were last updated in 2005, while physical-activity guidelines date from 2011. The causes of sarcopenia are complex and multifactorial, but one key factor is that muscle cells in older adults no longer respond as strongly to the muscle-building signals triggered by exercise and protein intake, a phenomenon known as anabolic resistance. That means protein guidelines optimized for middle-aged adults may not be adequate as you get older.

Current guidelines call for a daily intake of 0.8 grams of protein per kilogram for adults. Most Canadians hit that threshold with ease; for example, a Quebec study of older adults called Nutrition as a Determinant of Successful Aging (NuAge) found an average intake of 1.0 g/kg/day. But even that may not be enough, Oliveira says: Another study found that older adults eating 1.2 g/kg/day of protein lost 40 per cent less muscle over a three-year period than those eating the recommended 0.8 g/kg/day.

You might be relieved to hear that the creeping weight gain of middle age – a pound or two (0.5 to 1 kilogram) a year starting in your 20s, on average – eventually grinds to a halt. By the time you’re in your 50s, you’ll typically start slowly shedding weight.

Don’t celebrate yet, though. There’s a good chance that the weight you’re losing is muscle – precisely what you need to hang onto to stay metabolically healthy and independent into old age. The scientific term for this age-related loss of muscle, strength and physical function is “sarcopenia,” a condition that’s often overshadowed by the more urgent battle against obesity – and that oversight, according to a new review paper by Canadian researchers, has potentially serious consequences.

“The aging of the population is the epidemiological trend of our time,” says Camila Oliveira, a nutrition researcher at the University of Alberta. “We know that sedentary lifestyles, poor dietary patterns and increasing life expectancy will dramatically impact the prevalence of sarcopenia in the next decade.” In a forthcoming issue of the journal Applied Physiology, Nutrition, and Metabolism, Oliveira and her colleague Carla Prado, along with Isabelle Dionne of the University of Sherbrooke, argue that current Canadian nutrition and exercise guidelines are inadequate for preventing sarcopenia and don’t reflect the latest research on the topic. Guidelines for protein intake were last updated in 2005, while physical-activity guidelines date from 2011.

The causes of sarcopenia are complex and multifactorial, but one key factor is that muscle cells in older adults no longer respond as strongly to the muscle-building signals triggered by exercise and protein intake, a phenomenon known as anabolic resistance. That means protein guidelines optimized for middle-aged adults may not be adequate as you get older.

Current guidelines call for a daily intake of 0.8 grams of protein per kilogram for adults. Most Canadians hit that threshold with ease; for example, a Quebec study of older adults called Nutrition as a Determinant of Successful Aging (NuAge) found an average intake of 1.0 g/kg/day. But even that may not be enough, Oliveira says: Another study found that older adults eating 1.2 g/kg/day of protein lost 40 per cent less muscle over a three-year period than those eating the recommended 0.8 g/kg/day.

Actually changing nutrition and exercise guidelines is a lengthy and complicated process, Oliveira admits. Some of the machinations have already begun, and scientists are diligently trying to determine exactly what new recommendations should say. But the underlying message is straightforward: To age with grace and strength, Oliveira says, we need to “change the mindset that older adults should remain quiet and spare their energy to stay healthy.”


By Alex Hutchinson | Globe and Mail | Published October 8, 2018
The information contained is as of date of publication, and may be subject to change. These articles are intended as general information only.
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